Henry (Hal) Duncan is an Assistant Professor/Consultant in Endodontics in Dublin Dental University Hospital, Trinity College Dublin. He completed higher training in Guy’s Hospital, London and a PhD in the University of Birmingham in the area of epigenetics and pulpal-regeneration. He is currently the principal supervisor for several clinical and scientifically-trained PhD students, has received several research grants, written 14 book-chapters and edited 2-textbooks and has published widely internationally. His research is focused on developing novel therapeutic solutions, which will improve the diagnosis and outcome of treatment of decayed teeth and the damaged pulp. As a Fulbright-HRB HealthImpact Scholar, he will visit Rutger’s University, New Jersey to investigate potential novel roles for matrix metalloproteinase 13, a tissue-collagenase highly expressed in dental tissue during development and repair processes, with the aim of establishing mutually-beneficial collaborations between the U.S. and Ireland focused on the development of next-generation targeted therapeutic solutions for deep decay and toothache.